The Digestive Health Center of Excellence

The Cominelli Group
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Publications (selected, from 2000 to present)

Bamias G, Martin C, Mishina M, Ross WG, Rivera-Nieves J, Marini M, Cominelli F.
Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation.
Gastroenterology. 2005 Mar;128(3):654-66.
Cominelli F.  
Cytokine-based therapies for Crohn's disease--new paradigms.
N Engl J Med. 2004 Nov 11;351(20):2045-8.
Redlitz KH, Yamshchikov VF, Cominelli F.  
Differential contribution of IL-1Ra isoforms to allele-specific IL-1Ra mRNA accumulation.
J Interferon Cytokine Res. 2004 Apr;24(4):253-60.
Bickston SJ, Cominelli F.  
Optimal dosing of 5-aminosalicylic acid: 5 decades of choosing between politicians.
Clin Gastroenterol Hepatol. 2003 Jan;1(1):3-4.
Arseneau KO, Yeaton P, Kahaleh M, Cominelli F.  
Effect of digestive health care services integration on resource use and outcomes in patients with digestive disorders.
Clin Gastroenterol Hepatol. 2003 Mar;1(2):145-51.
Bamias G, Sugawara K, Pagnini C, Cominelli F.  
The Th1 immune pathway as a therapeutic target in Crohn's disease.
Curr Opin Investig Drugs. 2003 Nov;4(11):1279-86.
Bickston SJ, Comerford LW, Cominelli F.  
Future therapies for inflammatory bowel disease.
Curr Gastroenterol Rep. 2003 Dec;5(6):518-23.
Bamias G, Martin C 3rd, Marini M, Hoang S, Mishina M, Ross WG, Sachedina MA, Friel CM, Mize J, Bickston SJ, Pizarro TT, Wei P, Cominelli F.  
Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease.
J Immunol. 2003 Nov 1;171(9):4868-74.
Marini M, Bamias G, Rivera-Nieves J, Moskaluk CA, Hoang SB, Ross WG, Pizarro TT, Cominelli F.  
TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis.
Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8366-71.
Pizarro TT, Arseneau KO, Bamias G, Cominelli F.  
Mouse models for the study of Crohn's disease.
Trends Mol Med. 2003 May;9(5):218-22.
Rivera-Nieves J, Bamias G, Vidrich A, Marini M, Pizarro TT, McDuffie MJ, Moskaluk CA, Cohn SM, Cominelli F.  
Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis.
Gastroenterology. 2003 Apr;124(4):972-82.
Bamias G, Marini M, Moskaluk CA, Odashima M, Ross WG, Rivera-Nieves J, Cominelli F.  
Down-regulation of intestinal lymphocyte activation and Th1 cytokine production by antibiotic therapy in a murine model of Crohn's disease.
J Immunol. 2002 Nov 1;169(9):5308-14.
Yamshchikov VF, Mishina M, Cominelli F.
A possible role of IL-1ra 3'-untranslated region in modulation of protein production.
Cytokine. 2002 Jan 21;17(2):98-107.
Rivera-Nieves J, Bamias G, Alfert J, Bickston SJ, Moskaluk CA, Cominelli F.  
Intestinal ischemia and peripheral gangrene in a patient with chronic renal failure.
Gastroenterology. 2002 Feb;122(2):495-9.
Arseneau KO, Stukenborg GJ, Connors AF Jr, Cominelli F.  
The incidence of lymphoid and myeloid malignancies among hospitalized Crohn's disease patients.
Inflamm Bowel Dis. 2001 May;7(2):106-12.
Yamshchikov V, Mishin V, Cominelli F.  
A new strategy in design of +RNA virus infectious clones enabling their stable propagation in E. coli.
Virology. 2001 Mar 15;281(2):272-80.
Kosiewicz MM, Nast CC, Krishnan A, Rivera-Nieves J, Moskaluk CA, Matsumoto S, Kozaiwa K, Cominelli F.  
Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease.
J Clin Invest. 2001 Mar;107(6):695-702.
Bickston SJ, Cominelli F.  
Recombinant interleukin 10 for the treatment of active Crohn's disease: lessons in biologic therapy.
Gastroenterology. 2000 Dec;119(6):1781-3.
Pizarro TT, Arseneau KO, Cominelli F.  
Lessons from genetically engineered animal models XI. Novel mouse models to study pathogenic mechanisms of Crohn's disease.
Am J Physiol Gastrointest Liver Physiol. 2000 May;278(5):G665-9.